Liverpool XI vs Southampton: Confirmed team news, predicted lineup and injury latest for Carabao Cup

Arne Slot could hand starts to some youngsters at Anfield

Liverpool face Southampton in the Carabao Cup on Tuesday

Arne Slot is expected to name a much-changed Liverpool team for their Carabao Cup game against Southampton.

Virgil van Dijk, Ibrahima Konate, Ryan Gravenberch, Mohamed Salah and Dominik Szoboszlai will all be rested after Saturday’s 2-1 Merseyside derby win over Everton.

New £125million signing Alexander Isak could start up front in place of Hugo Ekitike, with Slot eager to get minutes into his legs.

Slot may take a look at some of the younger players in his squad including 18-year-old centre-half Giovanni Leoni, who was signed on deadline day for £26m from Parma.

Jeremie Frimpong will be looking to make an impression at right-back as he returns from injury.

There is also likely to be a change in goal with Georgi Mamardashvili set to get a start.

After scoring the winner against last month, 17-year-old winger Rio Ngumoha is also be pushing for a start.

With Liverpool top of the Premier league, Slot is likely to see this as the perfect opportunity to give fringe squad players Curtis Jones, Joe Gomez and Federico Chiesa a run out. All three have seen limited action so far this season.

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Wataru Endo is set to get a start in midfield.

Slot has never been afraid to giving young players a chance so it would not be a surprise to see significant action for Trey Nyoni and Jayden Danns, who featured in pre-season.

Predicted Liverpool XI: Mamardashvili, Frimpong, Gomez, Leoni, Robertson,Nyoni, Jones, Endo, Chiesa, Ngumoha, Isak

Time and date: 8pm BST on Tuesday, September 23, 2025

Venue: Anfield

How to watch: ITV and Sky Sports